Unraveling the Rare Connection: Rickets Syndrome and Secondary Osteoarthritis – An Intriguing Case Study
Armia Indra Nur Alam1, Muhammad Dezha Detiro2*
Abstract
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive destruction and loss of articular cartilage. Osteoarthritis of the knee can be divided into two types, namely primary and secondary. Primary osteoarthritis is articular degeneration without an obvious cause, while secondary osteoarthritis is a consequence of abnormal force concentration in the joint due to post-traumatic causes or abnormal articular cartilage, such as rheumatoid arthritis (RA). Rickets syndrome (rickets) is characterized by mineralization defects and widening of the epiphyseal plate. The mineralization defect that occurs in patients with rickets certainly affects bone and cartilage formation. These bone formation abnormalities can inhibit movement and cause pain. A patient came from the orthopedic clinic for consultation regarding knee pain since 6 months ago. This complaint arose starting with the patient fell on his right-side knee. Previously, the patient could walk, but because the patient had fallen and hit his right knee, the patient immobilized his knee for 3 months. After immobilization, the patient’s leg felt stiff, which made the patient unable to walk again. The patient previously had a rickets syndrome (rickets) disorder diagnosed by an orthopedic doctor since the patient was 6 years old. Patients with rickets syndrome have a higher risk of secondary osteoarthritis. This is due to mineralization defects that affect bone and cartilage growth. These growth abnormalities will affect bone strength and cartilage growth, so that even with minimal fractures can cause severe osteoarthritis in patients with rickets disorders.
Keywords
ricket syndrome; osteoatritis; mineralization defect; human and medicine.
Cite This Article
Alam, A. I. N., Detiro, M. D. (2025). Unraveling the Rare Connection: Rickets Syndrome and Secondary Osteoarthritis – An Intriguing Case Study. International Journal of Scientific Advances (IJSCIA), Volume 6| Issue 5: Sep – Oct 2025, Pages 956-962 URL: https://www.ijscia.com/wp-content/uploads/2025/10/Volume6-Issue5-Sep-Oct-No.957-956-962.pdf
Volume 6 | Issue 5: Sep – Oct 2025
