Ocular Abnormalities in Congenital Rubella Syndrome: A Literature Review
Aisyah Rahmah Salsabila1, Dwiyanti Puspitasari2*, Indri Wahyuni³, Rozalina Loebis³
Abstract
This literature review examines the epidemiology, clinical profile, diagnosis, and management of Congenital Rubella Syndrome (CRS), focusing on endemic regions. Despite global success in reducing cases to 32,000 by 2019, severe disparities persist, particularly in Southeast Asia. Indonesia reported 229 cases in 2021, constituting 57% of the total regional burden, highlighting critical immunization gaps. The clinical findings confirmed the CRS triad, with hearing impairment being the most prevalent sequela. Management is strictly preventative, as no curative treatment exists. Diagnosis relies on serological confirmation and early screening, given the high rate of diagnosis in the month age group. This review advocates for aggressive RCV campaigns for women of childbearing age, coupled with urgent neonatal screening protocols for auditory and ocular defects to ensure timely surgical and rehabilitative intervention, mitigating the lifelong developmental costs of the syndrome.
Keywords
congenital rubella syndrome; CRS; rubella; ocular abnormalities
Cite This Article
Salsabila, A. R., Puspitasari, D., Wahyuni, I., Loebis, R. (2025). Ocular Abnormalities in Congenital Rubella Syndrome: A Literature Review. International Journal of Scientific Advances (IJSCIA), Volume 6| Issue 6: Nov – Dec 2025, Pages 1056-1060 URL: https://www.ijscia.com/wp-content/uploads/2025/11/Volume6-Issue6-Nov-Dec-No.973-1056-1060.pdf
Volume 6 | Issue 6: Nov – Dec 2025
