Clinical Profile and Blood Pressure Patterns of Patients with Thyroid Dysfunction in Dr. Soetomo General Academic Hospital (2023–2024)

Muhammad Faiz Fadlyanputra¹, Hermawan Susanto^2*, Mochamad Yusuf³

Abstract

Introduction: Thyroid dysfunction is a common endocrine disorder characterized by abnormalities in thyroid structure or function, leading to disturbances in hormone production. It is the second most prevalent endocrine condition after diabetes mellitus and affects multiple organ systems. Changes in thyroid hormone levels influence metabolic rate, vascular resistance, and cardiac output, making blood pressure an important clinical parameter. Therefore, evaluating clinical characteristics and blood pressure is essential for improving assessment and management. Methods: This retrospective descriptive study examined 208 adult cases of thyroid dysfunction that met the inclusion and exclusion criteria. Variables assessed included age, gender, anthropometric data, blood pressure, TSH, and FT4 levels. Results: Of the 208 patients, 79.8% were female, with a mean age of 41.98 years. Hyperthyroidism was more common (69.2%), with overt hyperthyroidism as the most frequent subtype (42.8%). The mean BMI was 25.23 kg/m², with most patients classified as normal or overweight. Hypertension was the most prevalent blood pressure category (57.7%), with a higher proportion of hyperthyroid patients affected (60.4% vs. 51.6%). Mean systolic and diastolic blood pressure didn’t show any significant difference between thyroid groups. FT4 showed a weak positive correlation with diastolic pressure, while TSH showed no significant correlation. Conclusion: Thyroid dysfunction in this population predominantly affected women and young to middle-aged adults, with overt hyperthyroidism being the dominant presentation. Hypertension was frequent across thyroid groups, and weak correlations between thyroid levels and blood pressure suggest multifactorial influences. More comprehensive blood pressure monitoring and cardiovascular assessment remain important in patients with thyroid dysfunction.

Keywords

thyroid dysfunction; hyperthyroidism; hypothyroidism; blood pressure; hypertension; body mass index; clinical profile

Cite This Article

Fadlyanputra, M. F., Susanto, H., Yusuf, M. (2025). Clinical Profile and Blood Pressure Patterns of Patients with Thyroid Dysfunction in Dr. Soetomo General Academic Hospital (2023–2024). International Journal of Scientific Advances (IJSCIA), Volume 6| Issue 6: Nov – Dec 2025, Pages 1129-1134 URL: https://www.ijscia.com/wp-content/uploads/2025/11/Volume6-Issue6-Nov-Dec-No.985-1129-1134.pdf

Volume 6 | Issue 6: Nov – Dec 2025