Clinical Perspectives and Diagnostic Challenges of Adolescent Polycystic Ovarian Syndrome: A Literature Review

Nazwa Febry Savira¹, Bambang Purwanto^2*, Atika³

Abstract

Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder among females of reproductive age, increasingly recognized during adolescence. However, diagnosis at this stage remains challenging due to overlapping features with normal pubertal development. This review summarizes current evidence on the clinical characteristics, diagnostic challenges, and management of adolescent PCOS. Diagnosis should be based on both menstrual irregularity and hyperandrogenism, while avoiding premature reliance on polycystic ovarian morphology (PCOM) or anti-Müllerian hormone (AMH). Early recognition and holistic management through lifestyle modification, individualized pharmacologic therapy, and psychosocial support are essential to prevent long-term metabolic, reproductive, and psychological complications. Establishing well-defined diagnostic standards for menstrual irregularity and developing adolescent-specific thresholds are crucial to enhance diagnostic accuracy, ensure timely intervention, and improve overall quality of life among adolescents affected by PCOS.

Keywords

adolescent PCOS; menstrual irregularity; hyperandrogenism; diagnostic criteria; polycystic ovarian morphology; anti-Müllerian hormone; insulin resistance

Cite This Article

Savira, N. F., Purwanto, B., Atika. (2025). Clinical Perspectives and Diagnostic Challenges of Adolescent Polycystic Ovarian Syndrome: A Literature Review. International Journal of Scientific Advances (IJSCIA), Volume 6| Issue 6: Nov – Dec 2025, Pages 1251-1257 URL: https://www.ijscia.com/wp-content/uploads/2025/12/Volume6-Issue6-Nov-Dec-No.1002-1251-1257.pdf

Volume 6 | Issue 6: Nov – Dec 2025