Multiple Organ Dysfunction and The pSOFA Score in Critically Ill Children: A Narrative Review

Multiple Organ Dysfunction and The pSOFA Score in Critically Ill Children: A Narrative Review Saskia Putri Fadillah1, Arina Setyaningtyas2,5*, Pradana Zaky Romadhon3,6, Bambang Pujo Semedi4,5 Abstract Multiple organ dysfunction syndrome (MODS) is one of the medical conditions associated with morbidity and mortality in critically ill children. Organ damage develops through

Read More

RISUG as A Male Contraceptive: Breakthrough or Threat? A Review

RISUG as A Male Contraceptive: Breakthrough or Threat? A Review Kenley Nathanael1 , Reny I’tishom2 Abstract Background: Male contraceptive development has lagged behind female methods, creating a gap in available options. RISUG (Reversible Inhibition of Sperm Under Guidance) has emerged as a potential non-hormonal alternative. Reviews: This review examines both

Read More

Mechanisms of Dissemination and Clinical Features of Thoracic Metastases in Ovarian Cancer: A Literature Review

Mechanisms of Dissemination and Clinical Features of Thoracic Metastases in Ovarian Cancer: A Literature Review Khansa Kiasati Chandra Syahbunan1, Brahmana Askandar Tjokroprawiro2*, Arief Bakhtiar3, Grace Ariani4 Abstract This literature review explores the mechanisms of thoracic dissemination in ovarian cancer and the clinical features associated with thoracic metastases. Ovarian cancer remains

Read More

Colchicine in Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA): A Narrative Review

Colchicine in Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA): A Narrative Review Gavin Agza Chandralifio1, Hendri Susilo2* Abstract Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) is a heterogeneous clinical syndrome, accounting for 5–15% of myocardial infarction cases, characterized by myocardial injury in the absence of significant epicardial coronary obstruction. Unlike

Read More

The Role of Calcium Channel Blockers as Non‑Antiplatelet Therapy in MINOCA Patients: A Review of Current Clinical Evidence

The Role of Calcium Channel Blockers as Non‑Antiplatelet Therapy in MINOCA Patients: A Review of Current Clinical Evidence Carissa Adelia Putri1, Hendri Susilo2* Abstract Myocardial infarction with non-obstructive coronary arteries (MINOCA) represents a heterogeneous clinical entity with diverse underlying pathophysiological mechanisms. Recent evidence has demonstrated that MINOCA accounts for approximately

Read More

Clinical Profile and Blood Pressure Patterns of Patients with Thyroid Dysfunction in Dr. Soetomo General Academic Hospital (2023–2024)

Clinical Profile and Blood Pressure Patterns of Patients with Thyroid Dysfunction in Dr. Soetomo General Academic Hospital (2023–2024) Muhammad Faiz Fadlyanputra1, Hermawan Susanto2*, Mochamad Yusuf3 Abstract Introduction: Thyroid dysfunction is a common endocrine disorder characterized by abnormalities in thyroid structure or function, leading to disturbances in hormone production. It is

Read More