Clinical Efficacy and Comparison of Extracorporeal Shock Wave Therapy (ESWT) and Platelet-Rich Plasma (PRP) in Lateral Epicondylitis: A Systematic Review
I Gusti Lanang Agung Wiradinata1*, I Komang Gede Satria Mulyana Nugraha2, Kadek Yoga Premana3, I Wayan Restu Bela Susila3, Anak Agung Gde Duta Maha Putra3
Abstract
Background and Objectives: Lateral epicondylitis, or tennis elbow, is a common musculoskeletal condition caused by repetitive strain, particularly affecting the extensor carpi radialis brevis (ECRB) tendon. While often self-limiting, chronic cases can impair daily function. Among conservative treatments, platelet-rich plasma (PRP) and extracorporeal shock wave therapy (ESWT) are widely used. PRP provides biological regeneration through growth factor release, while ESWT offers mechanical stimulation to promote healing. However, their comparative effectiveness remains uncertain. Methods: A systematic review was conducted based on PRISMA-P guidelines. Searches were performed in PubMed, Scopus, and Cochrane Library to identify randomized controlled trials (RCTs) comparing PRP and ESWT in adults with chronic lateral epicondylitis. Outcomes of interest included pain (VAS) and function (PRTEE, DASH, HSG). Study quality was assessed using the JBI checklist. Results: Five RCTs met inclusion criteria, involving 17 to 63 participants and follow-up periods of 3 to 40 months. PRP showed gradual, long-term improvements in pain and function, with one study reporting a 93.85% success rate. ESWT provided more immediate pain relief within weeks. Discussion: Both PRP and ESWT are effective nonoperative treatments with distinct mechanisms and timelines. PRP is suited for long-term recovery, while ESWT offers faster symptom control. Despite promising outcomes, limitations include small sample sizes and variation in treatment protocols, underscoring the need for further research.
Keywords
extracorporeal shock wave therapy; lateral epicondylitis; platelet-rich plasma injection; tennis elbow.
Cite This Article
Wiradinata, I. G. L. A., Nugraha, I. K. G. S. M., Premana, K. Y., Susila, I. W. R. B., Putra, A. A. G. D. M. (2025). Clinical Efficacy and Comparison of Extracorporeal Shock Wave Therapy (ESWT) and Platelet-Rich Plasma (PRP) in Lateral Epicondylitis: A Systematic Review. International Journal of Scientific Advances (IJSCIA), Volume 6| Issue 4: Jul – Aug 2025, Pages 652-656 URL: https://www.ijscia.com/wp-content/uploads/2025/07/Volume6-Issue4-Jul-Aug-No.908-652-656.pdf
Volume 6 | Issue 4: Jul – Aug 2025
