Impact of Widal Test Accuracy on Typhoid Fever Management: A Literature Review
Ohikhuare Okun1*, Ohene Poku Agyemang2, Rapahel Udedike3, Omoikhoa Irele-Ifijeh4, Ufoma Adams Socrates5, Nnekachi Prayer Nnokam6
Abstract
The Widal test is a widely used diagnostic tool for typhoid fever, but its accuracy has significant implications for typhoid fever management. The test’s limitations, including false positives and negatives, can lead to misdiagnosis and inappropriate treatment, resulting in increased morbidity and mortality. The consequences of misdiagnosis are far-reaching, with delayed treatment contributing to the development of antibiotic resistance and increased risk of complications. This review examines the impact of Widal test accuracy on typhoid fever management, highlighting the need for careful interpretation of test results and awareness of test limitations. The development of more accurate diagnostic tests and strategies is crucial for improving the diagnosis and treatment of typhoid fever. This review provides a comprehensive overview of the Widal test’s role in typhoid fever diagnosis, its limitations, and the implications for clinical practice and future research. By understanding the limitations of the Widal test and working to improve diagnostic accuracy and treatment outcomes, healthcare providers can make a meaningful difference in the lives of patients with typhoid fever.
Keywords
Widal test; typhoid fever; diagnostic accuracy; misdiagnosis; antibiotic resistance.
Cite This Article
Okun, O., Agyemang, O. P., Udedike, R., Irele-Ifijeh, O., Socrates, U. A. (2025). Impact of Widal Test Accuracy on Typhoid Fever Management: A Literature Review. International Journal of Scientific Advances (IJSCIA), Volume 6| Issue 4: Jul – Aug 2025, Pages 781-783 URL: https://www.ijscia.com/wp-content/uploads/2025/08/Volume6-Issue4-Jul-Aug-No.929-781-783.pdf
Volume 6 | Issue 4: Jul – Aug 2025
