Phytochemical Potential of 70% Ethanol Extract of Gaharu Leaves (Gyrinops versteegii) Obtained by Maceration
Fitria Ramadhana1*, I Gusti Ayu Widianti², Ida Ayu Alit Widhiartini³
Abstract
Agarwood (Gyrinops versteegii) is a medicinal plant commodity that has been used ethnopharmacologically due to its broad spectrum of pharmacological activities, which are contributed by its rich secondary metabolite content. This study was conducted to determine the phytochemical potential of 70% ethanol extracts of agarwood leaves obtained through the maceration method. The methods used in this study included extraction, in which the pegagan leaf simplisia was extracted using 70% ethanol at a ratio of 1:10 for 24 hours, then evaporated to obtain a thick extract. The extract yield obtained was 13.35%. The analysis performed included qualitative and quantitative phytochemical tests. Qualitative phytochemical screening showed that the ethanol extract of agarwood leaves (Gyrinops verstegii) was positive for flavonoids, tannins, saponins, polyphenols, IC50, and antioxidant capacity. Quantitative testing using the UV-Vis spectrophotometry method showed total flavonoid levels of 62.12 mgQE/g, tannins of 66.90 mgQE/g, polyphenols of 28.177 mgGAE/g, an IC₅₀ value of 73.08 ppm, and antioxidant capacity of 19.13 ppm, which is classified as very strong. The results of this study indicate that 70% ethanol extract of agarwood leaves (Gyrinops verstegii) contains secondary metabolites that contribute to high antioxidant activity and have the potential to be further developed as a natural antioxidant agent.
Keywords
phytochemical screening; Gyrinops verstegii; maceration; 70% ethanol
Cite This Article
Ramadhana, F., Widianti, I. G. A., Widhiartini, I. A. A. (2026). Phytochemical Potential of 70% Ethanol Extract of Gaharu Leaves (Gyrinops versteegii) Obtained by Maceration. International Journal of Scientific Advances (IJSCIA), Volume 7| Issue 1: Jan – Feb 2026, Pages 185-189 URL: https://www.ijscia.com/wp-content/uploads/2026/02/Volume7-Issue1-Jan-Feb-No.1031-185-189.pdf
Volume 7 | Issue 1: Jan – Feb 2026

