The Effect of Rectal Irrigation Using A Combination of Metronidazole and Normal Saline on Histopathological Grades of Hirschsprung-Associated Enterocolitis Ni Nyoman Amik Indrayani Abstract Background: Rectal irrigation is utilized both as a treatment and preventive approach for Hirschsprung-associated enterocolitis (HAEC). Normal saline is frequently employed for rectal irrigation, while metronidazole,