Antibacterial Efficacy of Bromelain and Pineapple-Derived Extracts against Aggregatibacter actinomycetemcomitans and Streptococcus sanguinis: A Systematic Review Tania Saskianti*, Sindy Cornelia Nelwan2, Alda Winona Nur Ramadhani3, Choon Yee Fan4 Abstract Periodontal disease is a highly prevalent, biofilm-driven inflammatory condition, with severe periodontitis ranked among the most prevalent health conditions worldwide. Within